With nearly 50 expansions for Clinic: Deluxe Edition, the need for a way to ease players into that unwieldy pool of options has grown tremendously. This Clinic: Deluxe Edition - Campaign Book offers 3 campaign modes for all experience levels, and they are all designed for 1 - 4 players:

- The thematic campaigns: each of these campaigns facilitates learning the rules of the numerous expansions. The expansions are collected into 5 main themes and each theme is a separate campaign. Each campaign scenario introduces the expansions gradually (but cumulatively), easing the learning curve.

- The medium campaign: 8 scenarios, each combining a cross-section of 5 extensions of the 5 themes defined in the thematic campaigns.

- The Expert Campaign: 5 scenarios, each combining 8-9 expansions to tell a story (including Nathan Morse's actual story).